Pharmacological regulation of gene expression

Regulation of Gene Expression

For all living cells, regulation of gene expression by extracellular signals is a fundamental mechanism of development, homeostasis, and adaptation to the environment. Indeed, the ultimate step in many signal transduction pathways is the modification of transcription factors that can alter the expression of specific genes. Thus, neurotransmitters, growth factors, and drugs are all capable of al...

Regulation of Gene Expression

 Both prokaryotes and eukaryotes alter their patterns of gene expression in response to changes in environmental conditions.  In multicellular eukaryotes, each cell type contains the same genome but expresses a different subset of genes.  During development, gene expression must be carefully regulated to ensure that the right genes are expressed only at the correct time and in the correct pl...

Regulation of gene expression in tissue engineering, differentiation and bone regeneration of ossifying stem cells

Cells that make up the bodychr('39')s tissues are usually three-dimensional architecture, the threedimensional culture system enables cells to create natural and in vivo interactions which is an ideal environment for 3D (Three-dimensional) cell growth and issues such as exchange of similar food exchanges inside Capillary in living tissue. In tissue engineering discussion, cell scaffolding is hi...

The control of prostate-specific antigen expression and gene regulation by pharmacological agents.

Prostate-specific antigen is a serine protease that is a member of the kallikrein family. It is widely used as an indicator of tumor burden and as a surrogate marker for disease progression in men with androgen-independent prostate cancer. It has been shown that the expression and/or secretion of this glycoprotein can be regulated by pharmacological agents. The effects of these agents on PSA ma...

Epigenetic and pharmacological regulation of gene expression involved in senescence and tumor progression