Pharmacological PKA Inhibition: All May Not Be What It Seems
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چکیده
منابع مشابه
Pharmacological PKA inhibition: all may not be what it seems.
Signaling through the cyclic adenosine monophosphate-dependent protein kinase [protein kinase A (PKA)] is an important and widely studied area of signal transduction research. This signaling pathway is commonly investigated through the use of the pharmacological PKA inhibitors H89 and KT 5720. Both of these compounds are thought to block PKA actions through competitive inhibition of the adenosi...
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ژورنال
عنوان ژورنال: Science Signaling
سال: 2008
ISSN: 1937-9145
DOI: 10.1126/scisignal.122re4