Pharmacological interventions for painful diabetic neuropathy: Comparative analysis using network meta‐analysis

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Pharmacological interventions for painful diabetic neuropathy: Comparative analysis using network meta-analysis

Diabetic peripheral neuropathy is a common complication of diabetes mellitus that disturbs the quality of life of affected persons. Although diabetic neuropathy includes many types of different pathogeneses and clinical manifestations, the most common type is chronic sensorimotor distal symmetrical polyneuropathy. Among a variety of symptoms as a result of this type of neuropathy, neuropathic p...

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Pharmacologic interventions for painful diabetic neuropathy: an umbrella systematic review and comparative effectiveness network meta-analysis (Protocol)

BACKGROUND Multiple treatments for painful diabetic peripheral neuropathy are available. PURPOSE To evaluate the comparative effectiveness of oral and topical analgesics for diabetic neuropathy. DATA SOURCES Multiple electronic databases between January 2007 and April 2014, without language restriction. STUDY SELECTION Parallel or crossover randomized, controlled trials that evaluated pha...

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[Acupuncture for painful diabetic neuropathy].

In the present study I investigated the effects of acupuncture treatment on the pain of diabetic neuropathy and parsesthesia as well as the duration of the morbidity and treatment results. The study examined subjective symptoms associated with diabetic neuropathy (like spontaneous pain and parsesthesia) in 38 patients (divided into a 20-patient group treated with acupuncture and an 18-patient d...

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Painful Diabetic Neuropathy

N europathic pain exerts a substantial impact on quality of life, particularly by causing considerable interference in sleep, daily activities, and enjoyment of life. Chronic neuropathic pain is present in 13–26% of diabetic patients (1– 4). In a recent survey from Augsburg, Germany, the prevalence of painful polyneuropathy was found to be 13.3% in diabetic subjects, 8.7% in individuals with im...

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Painful diabetic neuropathy.

PDN is commonly caused by involvement of either the C fibres or the Aδ fibres. PDN caused by the involvement of small nerve fibers (C fibres), may present without objective clinical findings, such as decreased peripheral reflexes or abnormalities, on routine electrophysiological studies. Small fiber neuropathies may manifest as a number of different clinical symptoms, including allodynia, burni...

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ژورنال

عنوان ژورنال: Journal of Diabetes Investigation

سال: 2015

ISSN: 2040-1116,2040-1124

DOI: 10.1111/jdi.12354