PHARMACOLOGICAL ACTIVITIES OF 1,1-DIETHYL-2-METHYL-3-DIPHENYLMETHYLENEPYRROLIDINIUM BROMIDE (PYRODIFENIUM BROMIDE)

3-(2-Bromo­benz­yl)-1-methyl-1H-imidazol-3-ium bromide

In the title compound, C(11)H(12)BrN(2) (+)·Br(-), the imidazole and phenyl rings are nearly perpendicular, making a dihedral angle of 87.71 (7)°. The crystal structure is stabilized by non-classical inter-molecular C-H⋯Br hydrogen bonds and inversion-related mol-ecules are linked through π-π inter-actions between the imidazole ring systems [centroid-centroid distance = 3.472 (6) Å].

1-Methyl-3-n-tetra­decyl­imidazolium bromide monohydrate

In the title ionic liquid salt hydrate, C(18)H(35)N(2) (+)·Br(-)·H(2)O, the side chain in the cation has an extended conformation. The crystal structure is stabilized primarily by O-H⋯Br hydrogen bonds. C-H⋯O and C-H⋯Br inter-actions are also present.

Methyl bromide alternatives evaluated

Methyl bromide under fire.

Methyl Bromide under Fire Methyl bromide is one of the most widely used pesticides in the world, a broad-spectrum fumigant effective in controlling insects, nematodes, fungi, and bacteria. Methyl bromide is also highly toxic to humans. In December 1993, the EPA listed methyl bromide as a stratospheric ozone-depleting substance subject to phase-out. The final rule, issued 1 January 1994, freezes...

Methyl bromide poisoning.

Methyl bromide is a highly volatile liquid which disperses rapidly and readily. As a fumigant it ranks amongst the most efficient because of its extremely effective penetrating power and absence of fire or explosion hazard. It is, unfortunately, highly toxic and poisoning occurs readily in circumstances of careless or inadvertent exposure. Before 1940, only 42 cases of methyl bromide poisoning ...