Pharmacological account of Hibiscus Sabdariffa Linn.

Nootropic Activity of Calyces of Hibiscus Sabdariffa Linn

Nootropic acitivity of calyces of Hibiscus sabdariffa Linn. was studied in mice. Elevated plus maze and passive avoidance paradigm were employed to evaluate learning and memory parameters. Scopolamine (0.4 mg/kg, i.p.) was used to induce amnesia in mice. The aqueous extracts of calyces of Hibiscus sabdariffa (HS-100 and 200 mg/kg, p.o.) significantly attenuated amnestic deficits induced by scop...

Hibiscus sabdariffa L. - a phytochemical and pharmacological review.

Hibiscus sabdariffa L. (Hs, roselle; Malvaceae) has been used traditionally as a food, in herbal drinks, in hot and cold beverages, as a flavouring agent in the food industry and as a herbal medicine. In vitro and in vivo studies as well as some clinical trials provide some evidence mostly for phytochemically poorly characterised Hs extracts. Extracts showed antibacterial, anti-oxidant, nephro-...

Toxic effects of oral administration of extracts of dried calyx of Hibiscus sabdariffa Linn. (Malvaceae).

The effects of a 90-day oral administration of water and alcohol extracts of dried calyx of Hibiscus sabdariffa were evaluated in albino rats. Haematological, biochemical and histopathological changes were monitored every 30 days.The death of the animals was preceded by a severe loss in weight, accompanied with diarrhoea in animals on the 2000 mg/kg dose. There was an increase in food intake (g...

Toxicity and immunomodulatory activity of fractions of Hibiscus sabdariffa Linn (family Malvaceae) in animal models.

This study evaluated immunomodulatory properties and the sub-acute toxicity profile of two fractions of the aqueous alcoholic extract of the dried calyx of Hibiscus sabdariffa in experimental animals. Immunomodulatory activity was evaluated using red blood cell-induced immunostimulation. The fractions were not found to be toxic after 7-day administration, though there was severe weight loss wit...

Antimicrobial Activity of Hibiscus Sabdariffa (flowers)