Pharmacokinetics of calycopterin and xanthmicrol, two polymethoxylated hydroxyflavones with anti-angiogenic activities from Dracocephalum kotschyi Bioss
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چکیده
منابع مشابه
Two new monoterpene glycosides and trypanocidal terpenoids from Dracocephalum kotschyi.
From the whole plant of Dracocephalum kotschyi BOISS., two new monoterpene glycosides (9, 10), together with seven known terpenoids and a phytosterol (1-8), were isolated. Their structures were determined to be limonen-10-al (1), geranial (2), neral (3), beta-sitosterol (4), oleanolic acid (5), ursolic acid (6), p-mentha-8-en-1,2-diol (7), colosolic acid (8), limonen-10-ol 10-O-beta-D-glucopyra...
متن کاملAntiproliferative activity of flavonoids: influence of the sequential methoxylation state of the flavonoid structure.
Dracocephalum kotschyi Boiss. has been used as part of an ethnobotanical remedy against many forms of human cancer in Iran. It has been demonstrated that a flavonoid named xanthomicrol from D. kotschyi contributes to its preferential antiproliferative activity against malignant cells. In the present study, the antiproliferative activity of its flavonoid fraction was further characterized. Using...
متن کاملPhytochemical screening and evaluation of antioxidant activities of Dracocephalum kotschyi and determination of its luteolin content
OBJECTIVE Dracocephalum kotschyi (Lamiaceae family) has been used in traditional medicine for stomach and liver disorders, headache and congestion. In the present study, we have investigated phytochemical properties and antioxidant activities of dichloromethane, ethyl acetate and methanol extracts of D.kotschyi. MATERIAL AND METHODS Antioxidant activities of extracts were evaluated using the ...
متن کاملPhytochemical screening and evaluation of antioxidant activities of Dracocephalum kotschyi and determination of its luteolin content
Objective: Dracocephalum kotschyi (Lamiaceae family) has been usedin traditional medicine for stomach and liver disorders, headache and congestion. In the present study, we have investigated phytochemical properties and antioxidant activities of dichloromethane, ethyl acetate and methanol extracts of D.kotschyi. Material and Methods: Antioxidant activities of extracts were evaluated using the i...
متن کاملMonoterpene synthase from Dracocephalum kotschyi and SPME-GC-MS analysis of its aroma profile
Dracocephalum kotschyi (Lamiaceae), as one of the remarkable aromatic plants, widely grows and also is cultivated in various temperate regions of Iran. There are diverse reports about the composition of the oil of this plant representing limonene derivatives as its major compounds. There is no report on cloning of monoor sesquiterpene synthases from this plant. In the present study, the aroma p...
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ژورنال
عنوان ژورنال: DARU Journal of Pharmaceutical Sciences
سال: 2016
ISSN: 2008-2231
DOI: 10.1186/s40199-016-0161-x