PHARMACOKINETICS OF ALFENTANIL IN CHILDREN UNDERGOING SURGERY
نویسندگان
چکیده
منابع مشابه
Pain control with low-dose alfentanil in children undergoing minor abdominal and genito-urinary surgery.
BACKGROUND AND OBJECTIVE The aim of this study was to investigate the quality of intra- and postoperative analgesia obtained by alfentanil compared to that produced by peripheral blockade in children. METHODS During sevoflurane-nitrous oxide atracurium anaesthesia for minor abdominal or genito-urinary surgery, three groups of children aged 0-8 yr received 25 microg kg(-1) alfentanil intraveno...
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BACKGROUND The aim of this study was to provide a model-based analysis of the pharmacokinetics of remifentanil in infants and children undergoing cardiac surgery with cardiopulmonary bypass (CPB). METHODS We studied nine patients aged 0.5 to 4 years who received a continuous remifentanil infusion via a computer-controlled infusion pump during cardiac surgery with mildly hypothermic CPB were s...
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Objectives: Although paracetamol is a widely accepted and safe analgesic, guidelines regarding its definite analgesic dose are lacking. This study was, therefore, undertaken to compare the pharmacokinetics of paracetamol when administered by two routes, viz, intramuscular and rectal, in children undergoing minor surgery. Design: Randomized, controlled, assessor-blind, comparative clinical trial...
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We have studied the pharmacokinetics and effects of i.m. alfentanil as premedication for peribulbar block in 90 patients undergoing elective day-case cataract surgery. We compared alfentanil 12.5 micrograms kg-1 injected into the deltoid (n = 30) or gluteal muscle (n = 30) 15 min before the peribulbar block, and placebo (n = 30). The alfentanil concentrations were significantly greater in the d...
متن کامل1344159 - Pharmacokinetics of Tranexamic Acid in Patients Undergoing Cardiac Surgery
Introduction: Tranexamic acid (TXA) is routinely used during cardiac surgical procedures involving cardiopulmonary bypass (CPB) in order to reduce blood loss [1]. Although the optimum dose of TXA has been a subject of debate, a dosing regimen also sometimes referred to as the BART dose remains a popular choice for high-risk cardiac surgery [2]. The pharmacokinetics of TXA during the perioperati...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1987
ISSN: 0007-0912
DOI: 10.1093/bja/59.11.1437