Pharmacokinetics and pharmacodynamics of ceftizoxime in abscess fluid

Erratum to "Pharmacokinetics and penetration into tissue fluid of ceftizoxime in normal and hyperthemic sheep".

Erratum to `̀ Pharmacokinetics and penetration into tissue ̄uid of ceftizoxime in normal and hyperthemic sheep'' [Small Rumin. Res. 37 (2000) 43±49] Roberto Rule, RauÂl Lacchini, GermaÂn Quiroga, Laura Moreno, Perla de Buschiazzo ComisioÂn de Investigaciones Cientõ ®cas de la Provincia de Buenos Aires, CaÂtedra de Farmacologia, Facultad de MeÂdicina, U.N.L.P., Calle 60 y 120, 1900 La Plata, Arge...

Pharmacokinetics and penetration into tissue fluid of ceftizoxime in normal and hyperthermic sheep.

The pharmacokinetics of ceftizoxime was studied in six sheep before and after inducing hyperthermia using Escherichia coli endotoxin. Sheep implanted subcutaneously with cages of non-reactive material for collecting tissue cage fluid (TCF) were used to conduct two trials. In Trial 1 animals with normal basal temperature (normal sheep (NS)) were given intravenous (i.v.) and intramuscular (i.m.) ...

Pharmacokinetics and Pharmacodynamics of Gliclazide from Immediate and Modified Release Formulation Tablets in Rats

The objective of the study was to compare pharmacokinetic and pharmacodynamic parameters of gliclazide after administration of immediate (IR) and modified release (MR) tablets. The experiment included rats with both normoglyceamia and streptozocin (STZ)-induced hyperglyceamia. Several MR formulations were designed and in vitro drug release profile was assessed by a dissolution test. For the fur...

Pharmacokinetics and Pharmacodynamics of Gliclazide from Immediate and Modified Release Formulation Tablets in Rats

The objective of the study was to compare pharmacokinetic and pharmacodynamic parameters of gliclazide after administration of immediate (IR) and modified release (MR) tablets. The experiment included rats with both normoglyceamia and streptozocin (STZ)-induced hyperglyceamia. Several MR formulations were designed and in vitro drug release profile was assessed by a dissolution test. For the fur...

Pharmacokinetics/ Pharmacodynamics