Pharmacokinetic Properties of Rivaroxaban in Healthy Human Subjects
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منابع مشابه
Effects of Lemon and Seville Orange Juices on the Pharmacokinetic Properties of Sildenafil in Healthy Subjects
PURPOSE Several severe drug interactions have been reported when sildenafil, a potent drug for the treatment of erectile dysfunction, is co-administered with drugs or herbal remedies that inhibit cytochrome P450 (CYP) 3A4. This study evaluates the effects of two citrus fruit juices, lemon and Seville orange, on the pharmacokinetics of sildenafil in male healthy subjects following a single oral ...
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BACKGROUND Lesogaberan (AZD3355) is a novel reflux inhibitor developed as an add-on treatment to proton pump inhibitors (PPIs) for symptom relief in patients with gastroesophageal reflux disease who have a partial response to PPI therapy. OBJECTIVE The aim of this study was to evaluate the pharmacokinetic profile of lesogaberan in healthy subjects after single oral and intravenous administrat...
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Cefuroxime is a second-generation broad-spectrum cephalosporin antibiotic and is a mixture of two equally active isomers having 50% of each [1,2]. Cefuroxime is a bactericidal antibiotic that inhibits bacterial cell wall synthesis like other β–lactam antibiotics. As with other -lactam antibiotics, cefuroxime interferes with the transpeptidation process binding the cell wall, weakening the cell ...
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ژورنال
عنوان ژورنال: Cureus
سال: 2019
ISSN: 2168-8184
DOI: 10.7759/cureus.5484