Pharmacokinetic of furosemide in healthy subjects and relationship with diuretic action.
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15 صفحه اولFurosemide. A clinical evaluation of its diuretic action.
FUROSEMIDE (4 chloro-N[2-furyl methyl] -5-sulfamyl-anthranilic acid) (fig. 1) is a new and potent diuretic compound which is effective when given either orally or parenterally. Structurally it has in common with substituted thiazides a sulfamyl-benzene grouping. Animal studies have revealed it to be a most effective diuretic in both rats and dogs, resulting in maximum diuretic effects of up to ...
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The aim of this cross-over study was to investigate whether albumin infusion before furosemide administration could potentiate the diuretic action of furosemide. Seven patients with nephrotic syndrome were given the following infusions in random order on two separate days: 1) a sham solution followed by 160 mg of furosemide, 2) 100 ml of 20% human albumin followed by 160 mg of furosemide. Urine...
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ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 1987
ISSN: 1882-8272,0388-1601
DOI: 10.3999/jscpt.18.281