Pharmacokinetic interaction of Acacia catechu with CYP1A substrate theophylline in rabbits
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چکیده
منابع مشابه
Immunomodulatory activity of Acacia catechu.
The immunomodulatory effect of aqueous extract of Acacia catechu commonly known as Katha or Karangali was studied at two doses of 5 mg/kg and 50 mg/kg orally. The effect was studied in neutrophil adhesion test, mice lethality test, carbon clearance assay, cyclophosphamide induced neutropenia, serum immunoglobulin levels and the heamagglutination test. Acacia catechu extract showed an increase i...
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The effect of Positive End Expiratory Pressure (PEEP) on the hepatic elimination of low to moderate extraction ratio drugs has not been clearly defined. We prospectively investigated the effect of PEEP on the clearance of theophylline in 30 (20 males and 10 females) intubated critically ill adult patients with acute lung injury/acute respiratory distress syndrome (ALI/ARDS). The Mean (±SD) age ...
متن کاملPharmacokinetic Behavior of Theophylline following PEEP in Critically Ill Patients with Acute Lung Injury
The effect of Positive End Expiratory Pressure (PEEP) on the hepatic elimination of low to moderate extraction ratio drugs has not been clearly defined. We prospectively investigated the effect of PEEP on the clearance of theophylline in 30 (20 males and 10 females) intubated critically ill adult patients with acute lung injury/acute respiratory distress syndrome (ALI/ARDS). The Mean (±SD) age ...
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با به کار گیری روش گفتما ن شنا سی در تحقیق حا ضر گفتا ر میا ن آموزگا را ن و زبا ن آموزا ن در کلا سهای زبا ن انگلیسی در ایرا ن مورد بررسی قرار گرفت. ا هداف تحقیق عبا رت بودند از: الف) شنا سا ئی سا ختارهای ارتبا ط گفتا ری میا ن معلمین و زبا ن آموزا ن ب) بررسی تا ثیر نقش جنسیت دبیرا ن و زبا ن آموزان بر سا ختا رهای ارتبا ط گفتا ری میا ن آنها پ) مشخص کردن اینکه آ یا آموزگاران غا لب بر این ارتبا ط گف...
Pharmacokinetic study of the digoxin-acenocoumarol interaction in rabbits.
A study was carried out to evaluate the potential pharmacokinetic interaction between digoxin and acenocoumarol. The binding of digoxin to rabbit cardiac tissue homogenates was assessed in vitro, using the equilibrium dialysis technique. An increase in the first-order constant (p<0.05) and a reduction in the partition coefficient in the equilibrium situation (p<0.001) of digoxin were observed w...
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ژورنال
عنوان ژورنال: Journal of Traditional Chinese Medicine
سال: 2015
ISSN: 0254-6272
DOI: 10.1016/s0254-6272(15)30144-8