Pharmacokinetic and Pharmacodynamics Interaction between Syzygium cumini and Glipizide: Role of Cytochrome P450 Enzyme
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چکیده
منابع مشابه
Syzygium cumini : An overview
Aim of this article briefly focus on the potential phytochemicals and pharmacological activity of Syzygium cumini. Various parts of plant including seeds, bark, leaves and fruits had been studied and investigated for various pharmacological properties. The phytochemicals like malieic acid, oxalic acid, gallic acid, tannins, cynidin glycoside, oleanolic acid, flavonoids, essential oils, betulini...
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The Syzygium cumini (Myrtaceae) is a popular traditional medicinal plant in India. This study was intended to evaluate the antiinflammatory activity of ethyl acetate and methanol extracts of S.cumini leaves in carrageenan induced paw oedema in wistar rats at the dose level of 200 and 400 mg/kg administrated orally. Both the extracts exhibited significant anti-inflammatory activity, which suppor...
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Benzbromarone is a uricosuric drug and has been shown to be metabolized predominantly by cytochrome P450(CYP)2C9 in vitro findings. This study aims to investigate the influence of the CYP2C9 genotype on plasma levels of benzbromarone and 6-hydroxybenzbromarone, as well as uric acid lowering effects. A single oral dose pharmacokinetic and pharmacodynamic trial of benzbromarone (100 mg) was perfo...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Education and Research
سال: 2019
ISSN: 0019-5464
DOI: 10.5530/ijper.53.3s.97