Pharmacogenomic Testing to Select Antiplatelet Therapy

Ekaterina Lenk, Michael Spannagl Platelet Function Testing-guided Antiplatelet Therapy Platelet Function Testing-guided Antiplatelet Therapy

Cardiovascular diseases are the leading cause of death in the Western world. Several factors have led to the increase in vascular disorders, including the aging population, unhealthy lifestyles, increasing rates of diabetes and raised lipids, and further risk factors resulting in inflammation and calcification of the vascular endothelium. Activated platelets in damaged blood vessels can trigger...

Platelet Function Testing-Guided Antiplatelet Therapy

Cardiovascular diseases are the leading cause of death in the Western world. Several factors have led to the increase in vascular disorders, including the aging population, unhealthy lifestyles, increasing rates of diabetes and raised lipids, and further risk factors resulting in inflammation and calcification of the vascular endothelium. Activated platelets in damaged blood vessels can trigger...

Antiplatelet therapy and platelet function testing.

Eugene Braunwald,∗ Dominick Angiolillo,† Eric Bates,‡ Peter B. Berger,§ Deepak Bhatt,|| Christopher P. Cannon,∗ Mark I. Furman,¶ Paul Gurbel,∗∗ Alan D. Michelson,†† Eric Peterson,‡‡ Stephen Wiviott∗ ∗TIMI Study Group, Cardiovascular Division, Brigham and Women’s Hospital, Department of Medicine, Harvard Medical School, Boston, Massachusetts; †Department of Internal Medicine, University of Flori...

Pharmacogenomic Testing and Antithrombotic Therapy: Ready for Prime Time?

Pharmacogenomics is the study of an individual's interaction with a specific drug based upon the genetic make-up of the individual. Pharmacogenomic testing can be a powerful tool in testing a drug's potential efficacy and toxicity on an individual patient. For this tool to be used correctly, certain criteria have to be met. First and foremost is the strength of association between the genetic v...

Genetic testing in antiplatelet therapy – not effective for perioperative bleeding