منابع مشابه
OMMENTARY he Pharmacogenetics of Major Depression : Past , resent , and Future
uch has been said and written in recent years about the promise of pharmacogenetics. The vision is one of a world where we will be able to match medications with atients, maximizing efficacy while minimizing—or eliminatng—adverse effects. This vision has been widely embraced out f a real desire to better help patients. But we are now some ears into the pharmacogenetics enterprise, and we are be...
متن کامل[Pharmacogenetics of depression in elderly patients].
Depression is one of the leading causes of disability and is efficiently treated by antidepressant pharmacotherapy. Pharmacological treatment is still hampered by a delayed time of onset of clinical improvement and a series of side effects. In elderly, it is complicated by an increased risk of adverse drug events, associated with age-related physiological changes, individual variability in drug...
متن کامل[Major depression invites major concerns].
OBJECTIVE To overview limitations to the concept and construct of major depression. METHOD The objectives in initially conceptualizing major depression are examined against its subsequent utility and relevance to clinicians and researchers. RESULTS It is argued that, as defined, major depression does not differentiate clinical depression well from expressions of non-clinical depression or s...
متن کاملPrevention of major depression.
Before the 1980s, no randomized controlled trials had been carried out to test whether major depressive episodes could be prevented. In the past 30 years, several trials have reported success in reducing the incidence (the number of new cases) of major depressive episodes. These studies suggest that major depression can be prevented. Given the large burden of disease caused by major depression,...
متن کاملRaphe nuclei echogenicity changes in major depression
Background: Major depression is a common disorder with great social and individual burdens. Transcranial sonography (TCS) is a useful and noninvasive measure for assessment of normal and impaired brain parenchyma. The brainstem raphe nuclei are in close association with dorsocaudal limbic system and plays an important role in depression. In this study we compared the echogenicity of the r...
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ژورنال
عنوان ژورنال: Molecular Diagnosis & Therapy
سال: 2008
ISSN: 1177-1062,1179-2000
DOI: 10.1007/bf03256297