Pharmacogenetic Predictors of Statin-Mediated Low-Density Lipoprotein Cholesterol Reduction and Dose Response
نویسندگان
چکیده
منابع مشابه
Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response.
BACKGROUND There is interindividual variation in low-density lipoprotein cholesterol (LDLc) lowering by statins and limited study into the genetic associations of the dose dependant LDLc lowering by statins. METHODS AND RESULTS Five hundred nine patients with hyperlipidemia were randomly assigned atorvastatin 10 mg, simvastatin 20 mg, or pravastatin 10 mg (low-dose phase) followed by 80 mg, 8...
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ژورنال
عنوان ژورنال: Circulation: Cardiovascular Genetics
سال: 2008
ISSN: 1942-325X,1942-3268
DOI: 10.1161/circgenetics.108.795013