Pharmacogene Variation Consortium Gene Introduction: NUDT15

The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database

The Human Cytochrome P450 (CYP) Allele Nomenclature Database, a critical resource for the pharmacogenetics and genomics communities, has transitioned to the Pharmacogene Variation (PharmVar) Consortium. In this report we provide a summary of the current database, provide an overview of the PharmVar consortium, and highlight the PharmVar database which will serve as the new home for pharmacogene...

Introduction to 2010 ECDL Doctoral Consortium Issue

Introduction to the TPDL 2016 Doctoral Consortium

The TPDL 2016 Doctoral Consortium provided a high-quality international forum for Ph.D. students working in the areas related to the TPDL conference series to present their ongoing research and receive constructive feedback from a panel of prominent researchers from the TPDL community. It also provided a way to establish professional networks with other PhD students and more senior researchers ...

PharmGKB very important pharmacogene: SLCO1B1.

The solute carrier organic anion transporter family member 1B1 (SLCO1B1) gene encodes for a membrane-bound sodium-independent organic anion transporter protein (OATP1B1) that is involved in active cellular influx of many endogenous and xenobiotic compounds. SLCO1B1, formerly known by several other names including organic anion transporter 2 (OATP2), OATPC, liver-specific transporter 1 (LST1), a...

Gene Ontology Consortium: going forward

The Gene Ontology (GO; http://www.geneontology. org) is a community-based bioinformatics resource that supplies information about gene product function using ontologies to represent biological knowledge. Here we describe improvements and expansions to several branches of the ontology, as well as updates that have allowed us to more efficiently disseminate the GO and capture feedback from the re...