Pharmacodynamic Effects and Pharmacokinetic Profiles of Keto-Doxapram and Doxapram in Newborn Lambs
نویسندگان
چکیده
منابع مشابه
Prophylactic Effects of Doxapram, Ketamine and Meperidine in Postoperative Shivering.
BACKGROUND Postanaesthetic shivering is one of the most common unpleasant complications in patients. OBJECTIVES The aim of this study was to compare the efficacy of doxapram, ketamine and meperidine in prevention of shivering after anaesthesia. PATIENTS AND METHODS In this randomized, double-blind clinical trial, 120 patients aged between 20 - 45 years old under general anaesthesia were enr...
متن کاملThe ventilatory effects of doxapram in normal man.
1. To determine the mode of action of doxapram in man we have measured ventilation, oxygen uptake, CO2 production, hypoxic and hypercapnic ventilatory responses in six healthy men before and during intravenous infusion to maintain a constant plasma level. 2. Doxapram changed neither resting oxygen uptake nor CO2 production but produced a substantial increase in resting ventilation at both level...
متن کاملEffects of doxapram on postoperative pulmonary complications following thoracotomy.
An i.v. solution of 5% dextrose with doxapram 2 mg ml-1 or 5% dextrose alone was administered to 53 patients following lateral thoracotomy. Estimations of arterial PO2, PCO2 and pH were made before operation, during infusion and 7 days after after operation. Respiratory function tests were carried out before and 7 days after operation. There were no significant differences in arterial PO2, PCO2...
متن کاملeffect of bataine and sulphate supplement on wool and milk characteristics and lambs performance in naine ewes
تعداد 20 رأس میش نژاد نائینی 6+-24 ماهه، با میانگین وزن 2/3-+40 کیلوگرم، همراه با 20 رأس بره های آنها در قالب طرح کاملا تصادفی اثر بتائین و مکمل سولفات بر خصوصیات شیر و پشم و عملکرد بره ها بررسی شد. میش ها بطور تصادفی در چهار تیمار قرار گرفتند. تیمارها عبارت بودند از: 1-گروه شاهد 2-بتائین (05/0 درصد ماده خشک) 3-سولفات (24/0 سولفور درصد ماده خشک 4-بتائین هرماه با سولفات. جیره غذائی طبق nrc با مح...
15 صفحه اولPanic attacks induced by doxapram.
Doxapram is a respiratory stimulant thought to act by stimulating medullary neurones and carotid oxygen receptors (Kato and Buckley 1964). It changes neither oxygen uptake nor CO2 production, but produces substantial hyperventilation (Calvedey et al 1983). Hyperventilation occurs during naturally occurring or pharmacologically induced panic attacks, and perhaps also in panic patients between at...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pediatric Research
سال: 1990
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199008000-00013