Phage therapy for severe bacterial infections: a narrative review
نویسندگان
چکیده
منابع مشابه
Review: phage therapy: a modern tool to control bacterial infections.
The evolution of antibiotic-resistant in bacteria has aggravated curiosity in development of alternative therapy to conventional drugs. One of the emerging drugs that can be used alternative to antibiotics is bacteriophage therapy. The use of living phages in the cure of lethal infectious life threatening diseases caused by Gram positive and Gram negative bacteria has been reported. Another dev...
متن کاملPhage therapy of pulmonary infections
It is generally agreed that a bacteriophage-associated phenomenon was first unambiguously observed one-hundred years ago with the findings of Twort in 1915. This was independently followed by complementary observations by d'Hérelle in 1917. D'Hérelle's appreciation of the bacteriophage phenomenon appears to have directly led to the development of phages as antibacterial agents within a variety ...
متن کاملPhage therapy for severe infections tested in the first multicentre trial.
1384 www.thelancet.com/infection Vol 15 December 2015 It is common knowledge that antibiotic resistance is one of this century’s most important medical challenges. Journalists often speculate about a dystopian post-antibiotic future and, in 2014, the public chose combating it as the challenge for the £10 million Longitude Prize. Yet one potential alternative to antibiotics has been in clinical ...
متن کاملPhage Therapy: A Potential Alternative in the Treatment of Multi-Drug Resistant Bacterial Infections
Phages are viruses that infect the bacteria and causes bacterial cell lysis [1]. They are “programmed” to terminate one or a few kinds of different strains of bacteria. Phages are widespread in nature and can appear naturally in food and in the human body (for example in the intestines). Phages can efficiently destroy bacteria which have built up resistance over time to antibiotics and which ca...
متن کاملCommon Preconditions for Safe Phage Therapy of Pseudomonas aeruginosa Infections
One of the approaches to the treatment of infections caused by multiply-(MDR) or extra drugresistant (XDR) pathogenic strains may be application of bacterial viruses (bacteriophages)— phage therapy. Results of a long, but quite limited use of phage therapy in several Eastern European countries, as well as experiments on animal models in Western countries support the possibility to use phage the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medical Journal of Australia
سال: 2020
ISSN: 0025-729X,1326-5377
DOI: 10.5694/mja2.50355