PGR +331 A/G and Increased Risk of Epithelial Ovarian Cancer

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PGR +331 A/G and increased risk of epithelial ovarian cancer.

Childbearing and use of oral contraceptives are known to lower the risk of ovarian cancer, and it has been suggested that progesterone or progestin exposures play a role in these associations. The effects of progesterone may be mediated in part through the progesterone receptor, which exists in two functionally distinct protein isoforms, hPR-A and hPR-B. It is known that individuals carrying th...

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Short Communication PGR +331 A/G and Increased Risk of Epithelial Ovarian Cancer

Childbearing and use of oral contraceptives are known to lower the risk of ovarian cancer, and it has been suggested that progesterone or progestin exposures play a role in these associations. The effects of progesterone may be mediated in part through the progesterone receptor, which exists in two functionally distinct protein isoforms, hPR-A and hPR-B. It is known that individuals carrying th...

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ژورنال

عنوان ژورنال: Cancer Epidemiology Biomarkers & Prevention

سال: 2006

ISSN: 1055-9965,1538-7755

DOI: 10.1158/1055-9965.epi-06-0272