منابع مشابه
PFOS and PFOA Toxicological Overview
Toxic effects following repeated oral exposure includes effects on the liver, gastrointestinal and thyroid hormone effects Hepatotoxicity is the main effect reported in animals exposed to PFOS or PFOA via ingestion A small number of occupational studies have reported an association between exposure to PFOS or PFOA and several forms of cancer. Animals studies suggest that both PFOS and P...
متن کاملSerum Perfluorooctanoate (PFOA) and Perfluorooctane Sulfonate (PFOS) Concentrations and Liver Function Biomarkers in a Population with Elevated PFOA Exposure
BACKGROUND Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) persist in the environment and are found in relatively high concentrations in animal livers. Studies in humans have reported inconsistent associations between PFOA and liver enzymes. OBJECTIVES We examined the cross-sectional association between serum PFOA and PFOS concentrations with markers of liver function in adults...
متن کاملThe role of perfluooctanoic acid (PFOA) in airway hyperrepsoniveness
Objective/purpose Evidence is emerging that human exposure to environmentally ubiquitous perfluorooctanoic acid (PFOA), used commonly for its household stain repellency characteristics, is associated with immunologic changes. Data from adults near an industrial PFOA disposal site demonstrated a strong negative correlation between blood PFOA concentrations and some immune responses. We propose t...
متن کاملAssociation of Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonate (PFOS) with Uric Acid among Adults with Elevated Community Exposure to PFOA
BACKGROUND Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) are compounds that do not occur in nature, have been widely used since World War II, and persist indefinitely in most environments. Median serum levels in the United States are 4 ng/mL for PFOA and 21 ng/mL for PFOS. PFOA has been associated with elevated uric acid in two studies of chemical workers. Uric acid is a ri...
متن کاملREPRODUCTIVE TOXICOLOGY: Study Associates PFOS and PFOA with Impaired Fertility
Nanotechnology, the engineering of func tional materials at an atomic or molecular scale, has been among the fastest growing fields of science and technology. Worldwide sales of products incorporating nanotechnolo gy are projected to total $2.6 trillion by 2014, according to a 2004 report from Lux Research titled Sizing Nanotechnology’s Value Chain. But with the increasing use of nano materia...
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ژورنال
عنوان ژورنال: Environmental Science & Technology
سال: 2007
ISSN: 0013-936X,1520-5851
DOI: 10.1021/es0725697