Personalized risk prediction for type 2 diabetes: the potential of genetic risk scores
نویسندگان
چکیده
منابع مشابه
Advances in Risk Prediction of Type 2 Diabetes: Integrating Genetic Scores With Framingham Risk Models
Type 2 diabetes (T2D) is a worldwide epidemic affecting 8.3% of the current global adult population (1), with a growing prevalence in both developed and developing nations. It is estimated that of 29.1 million U.S. individuals with T2D, 8.1 million (27.8%) are undiagnosed—up from 7.0 million (27.1%) in 2010. T2D is strongly heritable, with estimates ranging from 30% to 70% (2). As elevated bloo...
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Type 2 diabetes (T2D) is a common disease caused by a complex interplay between many genetic and environmental factors. Candidate gene studies and recent collaborative genome-wide association efforts revealed at least 38 common single nucleotide polymorphisms (SNPs) associated with increased risk of T2D. Genetic testing of multiple SNPs is considered a potentially useful tool for early detectio...
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ژورنال
عنوان ژورنال: Genetics in Medicine
سال: 2016
ISSN: 1098-3600,1530-0366
DOI: 10.1038/gim.2016.103