Personalized HIV therapy to control drug resistance
نویسندگان
چکیده
منابع مشابه
Adherence to HIV drug therapy.
Antiretroviral therapy has dramatically improved the prognosis for many patients with HIV infection. For many patients who can navigate combinations of drugs and time their doses precisely, these drug regimens typically slow the progression of the disease and lengthen survival. But because these drug regimens are very complex, adherence--the degree to which patients follow medical advice in tak...
متن کاملPrevalence of HIV drug-resistance mutations in HIV-infected Mexican patients heavily experienced to antiretroviral therapy
Results We assessed 178 subjects, mean age (SD ±) of our subjects was 41.9 ± 11.9; 91% where male, who failed 2 to 15 ART regimen (median 5). CDC status was A 20%, B 21% and C 59%; 4% were coinfected with HBV and 2% were infected with HCV. Month median drug exposure was 121 (range 12-219). Ninety nine (55.6%) had triple class drug mutations, 170 (95.5%) had NRTI mutations, 113 (63.5%) had NNRTI...
متن کاملA delay-dependent model with HIV drug resistance during therapy
Article history: Received 25 April 2013 Available online 7 January 2014 Submitted by J. Shi
متن کاملOptimal adherence to antiretroviral therapy is critical to prevent HIV drug resistance (HIVDR)
1 Pharmacy refill adherence outperforms self-reported methods in predicting HIV therapy 1 outcome in resource-limited settings 2 Raphael Z Sangeda 3 [email protected] 4 5 Fausta Mosha 3 6 [email protected] 7 8 Mattia Prosperi, 9 [email protected] 10 11 Said Aboud 12 [email protected] 13 14 Jurgen Vercauteren 15 [email protected] 16 17 Ricardo J. Camacho 18 ricardojcamacho...
متن کاملHIV drug resistance in HIV-infected children.
Almeida et al. report, in this issue of the journal, a retrospective studyon theprevalence and patterns of antiretroviral drug resistance in 24 treatment-naïve and 23 treatment-experienced children failing therapy between 2000 and 2004 attending a clinic in São Paulo. All children were vertically infected, and the median age of the naïveand treatment-experienced children was 22 months and 102 m...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Drug Discovery Today: Technologies
سال: 2014
ISSN: 1740-6749
DOI: 10.1016/j.ddtec.2014.02.004