Persistent Changes in Vaginal Epithelium in Adult Mice Given Neonatal Injections of Deoxycorticosterone Acetate and Ovariectomized Soon Afterwards
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چکیده
منابع مشابه
The Effect of Hyperstimulation and Progesterone Injections on the Morphology of Mouse Vaginal Epithelium
Purpose: The aim of this study was to evaluate the morphological changes of vaginal epithelium after hyperstimulation and daily injection of progesterone followed ovarian hyperstimulation. Materials and Methods: Forty 8-10 week old virgin female mice were selected and divided in four groups. Two experimental groups were hyperstimulated using ip injection of 10 Iu of human menopasula gonadotrop...
متن کاملIntravenous injections in neonatal mice.
Intravenous injection is a clinically applicable manner to deliver therapeutics. For adult rodents and larger animals, intravenous injections are technically feasible and routine. However, some mouse models can have early onset of disease with a rapid progression that makes administration of potential therapies difficult. The temporal (or facial) vein is just anterior to the ear bud in mice and...
متن کاملCortical and medullary hemodynamics in deoxycorticosterone acetate-salt hypertensive mice.
The effect of acutely increasing renal perfusion pressure or extracellular fluid volume on renal medullary and cortical blood flow was examined in the low-renin deoxycorticosterone acetate (DOCA)-salt hypertension model in mice. A 50-mg DOCA tablet was implanted, and 1% saline was given as drinking water for 3 wk. Medullary and cortical blood flow were determined with laser-Doppler flowmetry, a...
متن کاملExtrarenal Na+ balance, volume, and blood pressure homeostasis in intact and ovariectomized deoxycorticosterone-acetate salt rats.
Water-free Na+ storage may buffer extracellular volume and mean arterial pressure (MAP) in spite of Na+ retention. We studied the relationship among internal Na+, K+, water balance, and MAP in Sprague-Dawley rats, with or without deoxycorticosterone-acetate (DOCA) salt, with or without ovariectomy (OVX). The rats were fed a low-salt (0.1% NaCl) or high-salt (8% NaCl) diet for 5 weeks. DOCA salt...
متن کامل[585 Cyclical Changes in the Vaginal Smear of Adult Ovariectomized Rats
According to Kostitch & Tele"bakovitch (1929), cyclical changes continue to occur in the vaginal smear of rats after removal of both ovaries. The following study was undertaken because of the important bearing this observation has on an understanding of the rhythmical changes which occur in the accessory reproductive organs, and because no reports of its confirmation have appeared in the litera...
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ژورنال
عنوان ژورنال: Proceedings of the Japan Academy
سال: 1966
ISSN: 0021-4280
DOI: 10.2183/pjab1945.42.156