Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart.
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چکیده
منابع مشابه
Bacterial Endotoxin Rapidly Stimulates Prolonged Endothelium-dependent Vasodilatation in the Isolated Perfused Rat Heart
2 Summary 1. The effects of bacterial lipopolysaccharide (Escherichia coli 0111-B4; LPS) on coronary vascular tone were examined in the isolated perfused rat heart. The role of nitric oxide and/or prostaglandin products of the cyclooxygenase pathway in mediating the actions of LPS were also investigated. 2. Coronary vascular tone was raised and maintained by a continuous perfusion of the thromb...
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Introduction: Beat-to-beat variation in heart rate shows a complex dynamics, and this complexity is changed during systemic inflammatory response syndrome (e.g. sepsis). It is not known whether or not cardiac pacemaker dynamical rhythm is affected by sepsis. The aim of this study was to investigate heart rate dynamics of isolated heart as well as expression of pacemaker channels (HCN) in a r...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1994
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.91.26.12383