Peroxisome Proliferator‐activated Receptors and their Relevance to Dermatology
نویسندگان
چکیده
منابع مشابه
Peroxisome proliferator-activated receptors and their relevance to dermatology.
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily and are expressed in a variety of tissues including skin and cells of the immune system. They act as ligand-dependent transcription factors which heterodimerize with retinoid X receptors to allow binding to and activation of PPAR responsive genes. Through this mechanism, PPAR ligands can ...
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Peroxisome proliferator-activated receptors (PPARs) are a member of nuclear receptors superfamily, which mainly regulate the expression of target genes involved in lipid and energy metabolism. These receptors are divided to three isotypes: PPARα, PPARγ and PPARβ/δ. Each isotype has a distinct tissue distribution relating to the distinct functions. In this study, the mRNA abundance for PPARα, PP...
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ژورنال
عنوان ژورنال: Acta Dermato-Venereologica
سال: 2005
ISSN: 0001-5555
DOI: 10.1080/00015550510030104