منابع مشابه
Exercise, Free Radical Metabolism, and Aging: Cellular and Molecular Processes.
1School of Life Sport and Social Sciences, Edinburgh Napier University, Edinburgh EH11 4BN, UK 2Laboratory of Integrated Physiology, University of Houston, 3855 Holman Street, Room 104 Garrison, Houston, TX 77204-6015, USA 3Sport and Exercise Science Research Institute, Ulster University, Jordanstown, Newtownabbey BT37 OQB, UK 4School of Sport and Exercise Sciences, Liverpool John Moores, Tom R...
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Plasma lipoproteins are responsible for carrying triglycerides and cholesterol in the blood and ensuring their delivery to target organs. Regulation of lipoprotein metabolism takes place at numerous levels including via changes in gene transcription. An important group of transcription factors that mediates the effect of dietary fatty acids and certain drugs on plasma lipoproteins are the perox...
متن کاملPEX11 promotes peroxisome division independently of peroxisome metabolism
The PEX11 peroxisomal membrane proteins are the only factors known to promote peroxisome division in multiple species. It has been proposed that PEX11 proteins have a direct role in peroxisomal fatty acid oxidation, and that they only affect peroxisome abundance indirectly. Here we show that PEX11 proteins are unique in their ability to promote peroxisome division, and that PEX11 overexpression...
متن کاملSirtuins, aging, and metabolism.
Sirtuins are nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylases that link protein acetylation, metabolism, aging, and diseases of aging. Sirtuins were initially found to slow aging in lower organisms and more recently shown to mediate many effects of calorie restriction on metabolism and longevity in mammals. This chapter focuses on two key mammalian sirtuins, SIRT1 (which r...
متن کاملEpigenetics and Cellular Metabolism
Living eukaryotic systems evolve delicate cellular mechanisms for responding to various environmental signals. Among them, epigenetic machinery (DNA methylation, histone modifications, microRNAs, etc.) is the hub in transducing external stimuli into transcriptional response. Emerging evidence reveals the concept that epigenetic signatures are essential for the proper maintenance of cellular met...
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ژورنال
عنوان ژورنال: Traffic
سال: 2010
ISSN: 1398-9219
DOI: 10.1111/j.1600-0854.2010.01144.x