Peroxidase Activities in Autonomously Functioning Nodules and Adjacent Non-Tumorous Portions of Thyroids.
نویسندگان
چکیده
منابع مشابه
Peroxidase activities in autonomously functioning nodules and adjacent non-tumorous portions of thyroids.
Peroxidase activities of autonomously functioning thyroid tumors (T) and surrounding non-tumorous tissue (N) in 5 patients were determined by employing guaiacol or iodide as the second substrates. The mean values for specific activities of T were 30 times (in iodide oxidation assay) or 4 times (in guaiacol oxidation assay) as high as those in N, being significantly higher than those of non-func...
متن کاملRarity of oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in Japan.
Constitutively activating mutations have recently been identified in the thyrotropin receptor (TSHR) of hyperfunctioning thyroid adenomas and familial hyperthyroidism. In the present study, we evaluated the frequency of constitutively activating TSHR mutations in a large series of autonomously functioning thyroid nodules (AFTNs) in Japan. Forty-five AFTNs (38 solitary hyperfunctioning thyroid a...
متن کاملOncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in the Japanese population.
OBJECTIVE Constitutively activating mutations of the thyrotropin receptor (TSHR) have been found in the majority of autonomously functioning thyroid nodules (AFTNs) in European patients. The reported frequency of these mutations varies among reports but amounts to 50-80%. To date, only one such mutation responsible for AFTNs has been identified in the Japanese population and the pathogenic role...
متن کاملComparative effects of thyroidal stimulants and inhibitors of normal and tumorous thyroids in xiphophorin fishes.
Spontaneous thyroid tumors in salmonid fishes, which appear to originate as simple hyperplasias, according to Marine and Lenhart (10, 11) and Marine (9), ultimately become invasive and re place fibrous connective tissue, muscle, and bone. Upon treatment with iodine these tumors will regress even after they have become invasive. It is interesting to compare the tumor in fish with thyroidal growt...
متن کاملHistometry of thyroids containing few and multiple nodules.
Histometric measurements were made on individual nodules and the internodular thyroid on glands from 15 patients without evidence of endocrine thyroid disease: some of the thyroids had multiple nodules. Measurements of the surviving internodular thyroid tissue showed that the various components were each within the normal range for thyroids from patients with no evidence of thyroid disease, but...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrinologia Japonica
سال: 1989
ISSN: 0013-7219,2185-6370
DOI: 10.1507/endocrj1954.36.635