Permeability of ocular vessels and transport across the blood-retinal-barrier
نویسندگان
چکیده
منابع مشابه
Passive permeability and outward active transport of fluorescein across the blood-retinal barrier in early ARM.
AIM To study the passive and active transport of fluorescein across the blood-retina barrier in early age related maculopathy (ARM) (soft drusen > 63 microm, hyperpigmentation and/or hypopigmentation in patients above 50 years of age). METHODS 15 patients and 10 healthy subjects were included. Morphological changes were graded from 30 degrees fundus photographs using a simplified version of t...
متن کاملStudies on the permeability of the blood-retinal barrier. IV. Junctional complexes of the retinal vessels and their role in the permeability of the blood-retinal barrier.
MAJNO, Palade, and Schoefl (1961), revising an old technique, demonstrated that colloidal carbon injected intravenously was a good indicator of increased vascular permeability and clearly labelled the particular vessels through which plasma protein was escaping. These authors, using this technique of vascular labelling and studying the rat cremaster muscle, found that the increase in permeabili...
متن کاملBlood-ocular barrier permeability in monkeys.
The permeability of the blood-ocular barrier was investigated in five monkeys using vitreous fluorophotometry (VFP). Inward permeability (Pin) of the blood-retinal barrier was calculated by a computer simulation method. Kinetic VFP was performed after intravitreal injection of fluorescein (F) or fluorescein monoglucuronide (FG). The estimated mean value of Pin (x10(-6) cm/min) was 4.8 (SD 1.2)....
متن کاملPermeability and patency of retinal blood vessels in experimental diabetes.
Increased permeability of retinal blood vessels in human diabetic retinopathy is well known clinically. Its morphologic equivalent is unknown. In dogs with 5 years of poorly controlled alloxan diabetes and nonproliferative diabetic retinopathy comparable to that of man, permeability and patency of retinal blood vessels were tested with the protein tracer horseradish peroxidase and evaluated by ...
متن کاملDeltorphin transport across the blood-brain barrier.
In vivo antinociception studies demonstrate that deltorphins are opioid peptides with an unusually high blood-brain barrier penetration rate. In vitro, isolated bovine brain microvessels can take up deltorphins through a saturable nonconcentrative permeation system, which is apparently distinct from previously described systems involved in the transport of neutral amino acids or of enkephalins....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Eye
سال: 1990
ISSN: 0950-222X,1476-5454
DOI: 10.1038/eye.1990.41