Peripheral Mechanisms in Appetite Regulation
نویسندگان
چکیده
منابع مشابه
Molecular Mechanisms of Appetite Regulation
The prevalence of obesity has been rapidly increasing worldwide over the last several decades and has become a major health problem in developed countries. The brain, especially the hypothalamus, plays a key role in the control of food intake by sensing metabolic signals from peripheral organs and modulating feeding behaviors. To accomplish these important roles, the hypothalamus communicates w...
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1. Newman, H. H., Freeman, F. N., and Holzinger, K. J. : Twins: A Study of Heredity and Environment. Chicago, Univ. Chicago Press, 1937. 2. Von Verschuer, 0. : Die vererbungsbiologische Zwillings-forschung. Ergebn. inn. Med. u. Kinderh., 31 :35, 1927. 3. Bauer, J. : Constitutio.i and Disease, 2nd Ed. New York, Grune & Stratton, 1945. 4. Ronv, H. R. : Obesity and Leanness. Philadelphia, Lea, 194...
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Patient consultations concerning weight problems are frequent but the over-all response to drug treatment is poor. There are many so-called anorexic drugs but the range of unwanted actions is even larger and often with distressing results. The costs to the National Health Service of doctors prescribing appetite-suppressant drugs exceeded E3.5 m in 1975 but there is little evidence of proportion...
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The hypothalamus is a center of food intake and energy metabolism regulation. Information signals from peripheral organs are mediated through the circulation or the vagal afferent pathway and input into the hypothalamus, where signals are integrated to determine various behaviors, such as eating. Numerous appetite-regulating peptides are expressed in the central nervous system and the periphera...
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Serotonin (5-HT), a mono-aminergic neurotransmitter is biochemically derived from tryptophan and is mainly found in gastrointestinal tract, platelets and central nervous system of animals. Serotonin (5-HT) in coordination with hypothalamus plays an important role in the CNS control of appetite, eating behavior, and energy balance and body weight. It has a special role in control of carbohydrate...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 2015
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2014.09.016