Peripheral giant cells granuloma as a rare early manifestation of primary hyperparathyroidism

Primary hyperparathyroidism occurs due to parathyroid adenoma, which as initial presentation in most cases includes recurrent nephrolithiasis (10-25%). Giant cell tumors (GDD) also called osteoclastomas or brown affect the second decade of life and are currently a rare manifestation primary hyperthyroidism. The incidence lesion appearance maxillary bones is 4.5%. We presented case 36 year old female patient with history hypertension, who developed an increase volume right region 4×3 cm, incapability complete occlusion dental arch, solid dysphagia, biopsy was performed peripheral giant cells granuloma result, PTH serum levels were requested, result 1175 pg/ml calcium 13.24 mg/dl. Parathyroid gammagram hyperfunctioning tissue. Patient underwent selective parathyroidectomy. She had adequate postoperative evolution discharged without complications. follow up by head neck surgery external consultation, 7.66 mg/dl, decrease 3×3 cm; pathology report adenoma. Surgical treatment tumor still pending maxillofacial department.