Perioperative risk assessment for successful kidney transplant in leigh syndrome: a case report

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Perioperative risk assessment for successful kidney transplant in leigh syndrome: a case report

BACKGROUND Leigh syndrome (LS) is a rare neurodegenerative mitochondrial disorder which typically presents in childhood but has a varied clinical course. Renal involvement such as proximal tubulopathy in patients with mitochondrial disorders has been described. However, end stage renal disease (ESRD) is uncommon and literature regarding patients undergoing kidney transplantation is limited. Suc...

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Leigh syndrome is a rare inherited neurometabolic subacute necrotizing encephalopathy mostly involving brainstem and basal ganglia, seen in the early childhood. It is characterized by progressive loss of mental and movement abilities associated with abnormal muscle tone, weakness, visual loss and respiratory failure. There is no effective treatment for this condition, as such the prognosis of t...

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ژورنال

عنوان ژورنال: BMC Nephrology

سال: 2018

ISSN: 1471-2369

DOI: 10.1186/s12882-018-0816-6