Pericardial Fat Is Associated With Prevalent Atrial Fibrillation

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Pericardial Fat Is Associated With Prevalent Atrial Fibrillation

Background—Obesity represents an important risk factor for atrial fibrillation (AF). We tested the hypothesis that pericardial fat, a unique fat deposit in close anatomic proximity to cardiac structures and autonomic fibers, is associated with prevalent AF. Methods and Results—Participants from the Framingham Heart Study underwent multidetector computed tomography from 2002 to 2005. We estimate...

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Pericardial fat is associated with prevalent atrial fibrillation: the Framingham Heart Study.

BACKGROUND Obesity represents an important risk factor for atrial fibrillation (AF). We tested the hypothesis that pericardial fat, a unique fat deposit in close anatomic proximity to cardiac structures and autonomic fibers, is associated with prevalent AF. METHODS AND RESULTS Participants from the Framingham Heart Study underwent multidetector computed tomography from 2002 to 2005. We estima...

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Pericardial fat is independently associated with human atrial fibrillation.

OBJECTIVES The purpose of this study was to investigate the association between atrial fibrillation (AF) and pericardial fat. BACKGROUND Pericardial fat is visceral adipose tissue that possesses inflammatory properties. Inflammation and obesity are associated with AF, but the relationship between AF and pericardial fat is unknown. METHODS Pericardial fat volume was measured using computed t...

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Commentary on: Pericardial Fat is Independently Associated with Human Atrial Fibrillation by Al Chekakie et al.

Obesity is an established risk factor for atrial fibrillation (AF).1 In fact, it has been reported that the increasing prevalence of obesity in the United States could account for up to 60 % of the increasing incidence of age and sex adjusted AF.2 Adipose tissue has been shown to be highly metabolically active and secretes several proinflammatory mediators; however, different fat depots differ ...

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Pericardial fat is associated with atrial fibrillation severity and ablation outcome.

OBJECTIVES The aim of this study was to characterize the relationship between pericardial fat and atrial fibrillation (AF). BACKGROUND Obesity is an important risk factor for AF. Pericardial fat has been hypothesized to exert local pathogenic effects on nearby cardiac structures above and beyond that of systemic adiposity. METHODS One hundred ten patients undergoing first-time AF ablation a...

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ژورنال

عنوان ژورنال: Circulation: Arrhythmia and Electrophysiology

سال: 2010

ISSN: 1941-3149,1941-3084

DOI: 10.1161/circep.109.912055