منابع مشابه
Peptides of the Pars Intermedia. Ciba Foundation Symposium 81
new directions in drug design are the contributions by Dr. Sartorelli and Dr. R.H. Abeles. Dr. Sartorelli's innovative approach to the development of bioreductive alkylating agents as chemotherapeutic agents for hypoxic tumor cell populations and Dr. Abeles's elegant mechanistic work on the design of specific "suicide inhibitors" of important enzymes exemplify the new wave of medicinal chemistr...
متن کاملThe Biosynthesis, Intracellular Transport, and Packaging of Melanocyte-stimulating Peptides in the Amphibian Pars Intermedia
Experiments in which glycine-(3)H has been introduced into excised neurointermediate lobes of Xenopus laevis incubated in a modified Krebs-Ringer bicarbonate medium have shown that approximately 50% of the incorporated radioactivity is present in small peptides which have an electrophoretic mobility characteristic of the melanocyte-stimulating (MSH) peptides shown to be elaborated within the ti...
متن کاملPituitary Pars Intermedia Dysfunction - Diagnosis
Although the frequency of diagnosis and treatment of pituitary pars intermedia dysfunction (PPID) in horses has clearly increased over the past decade, there is no evidence that the prevalence of PPID is actually increasing. Increased recognition of the disease is likely a consequence of clients maintaining their horses to more advanced ages as well as improved health care (e.g., diet and denti...
متن کاملPituitary pars intermedia dysfunction: equine Cushing's disease.
PPID in older equids has become a major health concern of horse owners. In response, equine practitioners have made greater efforts at understanding, diagnosing, and treating this disorder. Although PPID is recognized to be a different form of pituitary-dependent hyperadrenocorticism than is seen in canine or human patients, relatively little is known about the pathophysiology and natural progr...
متن کاملPituitary Pars Intermedia Dysfunction (Equine Cushing’s Disease)
Copyright ©NADIS 2017 Pituitary Pars Intermedia Dysfunction (PPID) is the correct term for the disease commonly known as Equine Cushing's Disease. The latter term is technically incorrect because it is now known that the disease is different from human Cushing's disease. It is a condition of older horses and typically develops in horses over 15 years of age although it can develop in younger an...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1982
ISSN: 0022-3050
DOI: 10.1136/jnnp.45.5.477-b