PEPTIDES AND BACTERIAL GROWTH

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Peptides and Bacterial Growth

Lactobacillus casei grows in the absence of vitamin Ba, provided that D-alanine and an unidentified peptide are added to a medium complete in other nutrients (1, 2). A partial hydrolysate of protein contained several chromatographically distinct fractions that possessed this “peptide factor” activity (3). It appeared likely that a single amino acid linked in a variety of combinations was respon...

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In previous reports (I, 2), data were presented on the growth response of a leucineless mutant (strain 679-680)’ of Escherichia coli strain K-12 to various L-leucine peptides. Measurement of the extent of bacterial growth after 24 hours incubation showed that, at low concentrations, the peptides were almost as effective in the stimulation of growth as was L-leucine; at high concentrations, howe...

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Novel Synthetic Amino Acids and Peptides as Bacterial Growth Inhibitors

The influence of novel synthetic amino acids and peptides on the growth of bacteria included in test culture collection has been studied. The compounds were revealed to inhibit the growth of all the strains included in collection. Some compounds demonstrated antibacterial activity in relation to antibiotic-resistant E.coli strains, others demonstrated the specificity in relation to particular s...

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Mucosal surfaces are habitats for the physiological microflora and are closely related to the mucosal immune compartment (mucosa-associated lymphoid tissue, MALT). Recently, considerable evidence has been accumulated showing that defined members of the physiological microflora express/liberate low molecular weight substances (peptides) which apparently are essential for the adequate immune resp...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1952

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)55634-9