Peptide-Mediated Cellular Uptake of Cryptophane
نویسندگان
چکیده
منابع مشابه
Nanolipoparticles-mediated MDR1 siRNA delivery: preparation, characterization and cellular uptake
Objective(s): Lipid-based nanoparticles (NLP) are PEGylated carriers composed of lipids and encapsulated nucleic acids with a diameter less than 100 nm. The presence of PEG in the NLP formulation improves the particle pharmacokinetic behavior. The purpose of this study was to prepare and characterize NLPs containing MDR1 siRNA and evaluate their cytotoxicity and cellular uptake. MDR1 siRNA coul...
متن کاملTat peptide mediated cellular uptake of SiO2 submicron particles.
Internalization of nano- and microparticles into live cells correlates closely with their potential applications, functions, cytotoxicity and intracellular drug delivery. Particularly, delivery of a large variety of cargoes such as proteins, peptides, nucleic acids and small particles into cells could be enhanced by some ligands such as Tat peptide. In this work, the ability of Tat mediated cel...
متن کاملPeptide-mediated cellular delivery.
Peptide-mediated molecular therapeutic delivery systems have recently emerged as an alternative means to effectively substitute or augment present gene therapy technologies, e.g., TAT, VP22, engineered peptides. These systems show great promise for the elimination of the main bottleneck to safe, efficient, targeted gene therapy delivery and are able to efficiently introduce DNA, antisense pepti...
متن کاملnanolipoparticles-mediated mdr1 sirna delivery: preparation, characterization and cellular uptake
objective(s): lipid-based nanoparticles (nlp) are pegylated carriers composed of lipids and encapsulated nucleic acids with a diameter less than 100 nm. the presence of peg in the nlp formulation improves the particle pharmacokinetic behavior. the purpose of this study was to prepare and characterize nlps containing mdr1 sirna and evaluate their cytotoxicity and cellular uptake. mdr1 sirna coul...
متن کاملReceptor-mediated cellular uptake of cyclosporine.
THE PROCESS of cellular uptake and metabolism of cyclosporine (CsA) is poorly understood. Earlier studies in this laboratory indicated that transport of CsA in blood occurs in association with plasma lipoproteins, with low density lipoprotein (LDL) and high density lipoprotein (HOL) carrying about 32% each of the total CsA in blood. This observation suggests the possibility that the cellular up...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bioconjugate Chemistry
سال: 2008
ISSN: 1043-1802,1520-4812
DOI: 10.1021/bc8002265