Peptic Ulcer Diseases in Korea

Peptic Ulcer Diseases in Korea

Peptic ulcer disease (PUD) is one of the most commonly encountered gastroenterologic diseases in Korea. The trend in diagnosis and treatment of PUD in Korea has changed in the past decade with the introduction of endoscopy and potent acid suppressants such as proton pump inhibitors. The discovery of Helicobacter pylori has opened a new era for the understanding of pathogenesis and management of...

Peptic Ulcer Diseases: Genetics, Mechanism, and Therapies

1Division of Hepato-Gastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 123 Ta-Pei Road, Niao-Sung District, Kaohsiung City 833, Taiwan 2Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital and Kaohsiung Medical University, Kaohsiung City 807, Taiwan 3Division of ...

Clinical characteristics of peptic ulcer perforation in Korea

AIM To elucidate the epidemiological characteristics and associated risk factors of perforated peptic ulcer (PPU). METHODS We retrospectively reviewed medical records of patients who were diagnosed with benign PPU from 2010 through 2015 at 6 Hallym university-affiliated hospitals. RESULTS A total of 396 patients were identified with postoperative complication rate of 9.1% and mortality rate...

[Helicobacter pylori infection in peptic ulcer and gastric cancer diseases].

胃 お よ び 十 二 指 腸 潰 瘍 は消 化 性 潰 瘍 と呼 ば れ て お り,日 本 人 で は特 に 胃潰 瘍 の頻 度 が 高 い.そ の 原 因 と して 「no acid no ulcer」 と言 わ れ る よ う に,胃 酸 が そ の主 役 を つ とめ,ス トレ ス,非 ス テ ロ イ ド系 消 炎 鎮 痛 剤 な どが 発 生 の脇 役 を つ とめ る と理 解 され て きた.現 在 で も,H2-プ ロ ッカ ー,プ ロ トンポ ン プ ・有 ン ヒ ビ ター(PPDに 代 表 され る, 胃酸 分 泌 抑 制 剤 が 潰 瘍 治 療 の 中 心 で あ り,粘 膜 保 護 剤 で 潰 瘍 治 癒 を促 進 させ る と い う治 療 法 に は 変 わ りが な い.ま た,H2-プ ロ ッ カ ー の登 場 は 潰 瘍 外 科 治 療 を激 変 ...

Peptic Ulcer