منابع مشابه
Utility of minor determinants in penicillin allergy skin testing
Background Penicillin allergy is a major concern among patients and physicians. There’s an estimated 5-10% self reported history of penicillin allergy by patients, but vast majority are not true hypersensitivities. Complete penicillin skin test with both major, minor determinants and amoxicillin is the test of choice for diagnosing IgE-mediated penicillin allergy. While Penicilloyl polylysine (...
متن کاملPenicillin allergy: anti-penicillin IgE antibodies and immediate hypersensitivity skin reactions employing major and minor determinants of penicillin.
300 children considered to have had adverse reactions to penicillin were examined. Informed consent was obtained from the parents. Skin tests were conducted by the scratch/prick and intradermal techniques, using benzylpenicilloyl polylysine conjugate and a mixture of minor determinants of penicillin. Specific anti-penicillin IgE antibodies were estimated by the radioallergosorbent test. There w...
متن کاملA retrospective comparison of false negative skin test rates in penicillin allergy, using pencilloyl-poly-lysine and minor determinants or Penicillin G, followed by open challenge
BACKGROUND A history of penicillin allergy in patients is common, but only 10-15 % are truly allergic. While the gold standard for diagnosing penicillin allergy is challenge, it is not recommended that this be done without first carrying out diagnostic skin testing. This is carried out with the major determinant benzylpenicilloyl (PPL) and the minor determinant mixture (MDM), consisting of peni...
متن کاملMinor identities for quasi-determinants and quantum determinants
We present several identities involving quasi-minors of noncommutative generic matrices. These identities are specialized to quantum matrices, yielding q-analogues of various classical determinantal formulas.
متن کاملDiagnosing penicillin allergy in the absence of minor determinant mixture
Background Penicillin allergy is a common presentation in allergy clinic. The diagnosis of immediate hypersensitivity is made using clinical history, skin testing, specific IgE levels and oral challenge. Skin testing is done using benzyl penicilloyl-polylysine (PPL) and a minor determinant mixture (MDM) consisting of penicillin byproducts. Although using PPL and MDM is considered first line for...
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ژورنال
عنوان ژورنال: Annals of Allergy, Asthma & Immunology
سال: 2018
ISSN: 1081-1206
DOI: 10.1016/j.anai.2018.09.459