PENICILLIN ANTIBODY

Acute haemolytic anaemia due to IgM penicillin antibody in a 3-year-old child: a sequel to oral penicillin.

A hitherto undescribed form of immune haemolytic anaemia due to penicillin antibody is described. The antibody, which was of the IgM class, fixed complement and caused acute haemolysis. Oral penicillin seems to have been responsible both for antibody production and, on subsequent exposure, for the haemolytic anaemia.

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Penicillin

By SIR ALEXANDER FLEMING, F.R.C.S., F.R.C.P., F.R.S. from the Inoculation Department, St. Mary's Hospital I HAVE in the last few years received a certain number of honours, but none has touched me more than the invitation to deliver the Robert Campbell Oration for thtis year in Belfast. I did not know Robert Campbell personally, but I have read much about him and have appreciated my great misfo...

Penicillin Therapy

Benzyl Penicillin

The search for an orally administered and stable penicillin preparation with high therapeutic efficacy led to the recent discovery that the benzyl ester of penicillin, given orally, was at least equal in protective effect to the equivalent weight of sodium penicillin administered parenterally to mice that had received lethal doses of pneumococci and hemolytic streptococci by intraperitoneal inj...