PENGARUH PEMBERIAN D-GALAKTOSA TERHADAP BERAT BADAN MENCIT BETINA

Experimental animals are that developed so they can be used as model in an experiment for the development of various fields science, especially field medical science. Aging is accumulation changes occur cells and tissues along with increasing age, pose a risk disease death. One signs aging weight gain. more quickly, this due to factors. them free radical factor. Administration d-galactose induce generalized organ systems. 6 weeks row causes increase galactose body. Giving mice will cause oxidative stress aging. So body sign needs studied. The study was conducted pharmacology laboratory Faculty Medicine, University North Sumatra total sample female average 20-35 grams. Mice were injected d-galactoa much 150 mg/kgBW once every day weeks. weighed weekly results experienced significant p value <0.005. This happened because continuous administration resulted tissue mice.