PENGARUH KONSENTRASI HYDROXYPROPYL METHYLCELLULOSE SEBAGAI BAHAN PENGIKAT PADA SEDIAAN TABLET EKSTRAK RIMPANG JAHE MERAH (zingiber officinale Var. Rubrum.)

نویسندگان

چکیده

Lozenges are solid preparations made from aromatic and sweet taste that can dissolve slowly in the mouth, which intended to treat infections mouth throat. Hydroxypropyl Methylcellulose (HPMC) is a binder be used lozenges.This study attempted examine effect of concentration HPMC as tablet preparation red ginger rhizome extract (Zingiber officinale Var Rubrum) by wet granulation method. This was laboratory experimental comparing three concentrations each formula i.e., FI (4%), FII (5%), FIII (6%).The resulting tablets were tested for physical properties including organoleptic tests, weight uniformity, hardness, friability hedonic tests. Based on results study, it shown with an increase binder, quality also increased. The higher used, better uniformity high level hardness. However, will decrease. showed 4%, 5%, 6% had whichwas fragility. Further, II 5% preferred respondentsbased

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ژورنال

عنوان ژورنال: Indonesian Journal of Pharmaceutical Education

سال: 2021

ISSN: ['2775-3670']

DOI: https://doi.org/10.37311/ijpe.v1i3.11667