Pendred's Syndrome in Two Families Living in Endemic Goitre Area

Endemic goitre in Guinea.

The prevalence of endemic goitre in the Tinjar area, Sarawak.

On questioning 126 households, only 9 (7.1 percent) used iodized salt whilst 74 (58.7 percent) households used only uniodized coarse salt and 7 (5.6 percent) used only uniodized fine salt. The remaining 36 (28.6 percent) households used both fine and coarse uniodized salt. Undoubtedly at this point in time legislation on "table" salt iodization must be interpreted to mean not only the iodizatio...

Endemic Goitre in Greece: Family Studies.

The evidence implicating iodine deficiency in the aetiology of endemic goitre is overwhelming, and a deficiency of iodine in the diet has been accepted as the main cause of this condition (Kelly and Snedden, I960; Greer, I962; Wayne, Koutras, and Alexander, I964). Considerations of the quantitative aspects of iodine metabolism leave little doubt that in the presence of a sufficiently severe and...

Pathophysiology of Himalayan endemic goitre.

The mountain slopes of the Himalayas, Alps, Pyrenees, and Andes have been the world’s most notorious foci of endemic goiter (1). The northern frontiers of India extending from Kashmir in the west to Assam in the east form an extensive Himalayan goiter belt (2). Forty million persons are believed to be exposed to the risk ofgoiter in this belt and approximately nine million are afflicted with it...

The Problem of Endemic Goitre.

The first is the classical type prevalent in mountainous regions, such as the Alps and Himalayas, occurring as a colloid-poor diffuse parenchymatous goitre in childhood, and as an adeno-parentchymatouts, nodular goitre, with its degenerative forms in adults. The second is the difJuse colloid goitre prevalent in lowland regions, such as the plains of Central Europe, and in England. The geographi...