Pegylated interferon, but not conventional interferon therapy induced severe skin lesions

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 Pegylated interferon, but not conventional interferon therapy induced severe skin lesions.

Correspondence and reprint request: Dr. Fanpu Ji, M.D. The second affiliated hospital, College of Medicine, Xi’an Jiaotong University, 157 Xi Wu Road, Xi’an 710004, Shaanxi Province, PR. China. Tel.: +86-29 8767-9275 Fax: +86-29 8767-9275 E mail: [email protected] Manuscript received: Octobre 4, 2011. Manuscript accepted: November 27, 2011. July-August, Vol. 11 No.4, 2012: 570-571 LETTER TO E...

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Face skin hyperpigmentation during pegylated interferon and ribavirin therapy.

Cutaneous hyperpigmentation may be caused by a number of diseases, such as Addison’s disease, scleroderma, haemochromatosis, Peutz-Jeghers syndrome, lichen planus, and adverse reactions to some medications such as oral contraceptives, cyclophosphamide, chloroquine, minocycline, bleomycin, ketoconazole and methyldopa (1). Hyperpigmentation of the tongue, face and body skin is a rare adverse effe...

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Effect of pegylated interferon

Objectives: To assess whether a combination of pegylated interferon (interferon conjugated with polyethylene glycol) and ribavirin can improve the response rate in patients with chronic hepatitis C who either did not respond to (Non-responders), or had relapsed after responding to (Relapsers) standard interferon and ribavirin combination therapy. Patients and methods: In this prospective study,...

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INTERFERON INDUCED CARDIOMYOPATHY: CASE REPORTS

There are few reports concerning interferon induced myocardial dysfunction. A known case of multiple myeloma who was receiving interferon alpha (IFA) for 14 months was brought to the emergency room in frank: pulmonary edema. After treatment of heart failure and discontinuation of interferon alpha, he remained asymptomatic thereafter. Another case of chronic active hepatitis on IFA complain...

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ژورنال

عنوان ژورنال: Annals of Hepatology

سال: 2012

ISSN: 1665-2681

DOI: 10.1016/s1665-2681(19)31475-9