Peanut Allergens Alter Intestinal Barrier Permeability and Tight Junction Localisation in Caco-2 Cell Cultures1
نویسندگان
چکیده
منابع مشابه
Peanut allergens alter intestinal barrier permeability and tight junction localisation in Caco-2 cell cultures.
BACKGROUND/AIMS Allergen absorption by epithelia may play an important role in downstream immune responses. Transport mechanisms that can bypass Peyer's patches include transcellular and paracellular transport. The capacity of an allergen to cross via these means can modulate downstream processing of the allergen by the immune system. The aim of this study was to investigate allergen-epithelial...
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BACKGROUND The intestinal tract plays an important role in food allergy and the intestinal mucosa barrier is critical for maintenance of its function. The underlying mechanisms of how food allergens modulate the intestinal permeability in inducing intestinal food allergy remain elusive. OBJECTIVE The aim of this study was to explore the mechanism of how food allergens influence the function o...
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ژورنال
عنوان ژورنال: Cellular Physiology and Biochemistry
سال: 2014
ISSN: 1421-9778,1015-8987
DOI: 10.1159/000362956