PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation
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چکیده
منابع مشابه
PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation
The Notch/CSL pathway plays an important role in skin homeostasis and carcinogenesis. CSL, the key effector of canonical Notch signaling endowed with an intrinsic transcription repressive function, suppresses stromal fibroblast senescence and Cancer Associated Fibroblast (CAF) activation through direct down-modulation of key effector genes. Interacting proteins that participate with CSL in this...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2016
ISSN: 1949-2553
DOI: 10.18632/oncotarget.11227