PD18-10 OPTIMAL SUBCLASSIFICATION SYSTEM FOR INTERMEDIATE-RISK NON-MUSCLE INVASIVE BLADDER CANCER
نویسندگان
چکیده
منابع مشابه
Treatment of Intermediate-Risk Non–Muscle-Invasive Bladder Cancer (NMIBC)
Objectives: Review treatment of NMIBC, particularly intermediate-risk NMIBC. Methods: Search of published literature on conventional adjuvant treatment of low-, intermediate-, and high-risk NMIBC, and novel treatment modalities. Results: A considerable percentage of patients with intermediate-risk NMIBC, and especially high-risk NMIBC, are at risk of disease recurrence and progression. Of curre...
متن کاملAdjuvant Treatment of Intermediate Risk Non-muscle Invasive Bladder Cancer
Despite continuous improvement of diagnosis, surgical and adjuvant treatment procedures for non-muscle invasive bladder cancer (NMIBC), their natural development is still influenced by the high rates of tumor recurrence and progression. The study aims at assessing the value of adjuvant intravesical chemotherapy within the therapeutic protocol for operated intermediate risk non-muscle invasive b...
متن کاملGenomic characterization of high-risk non-muscle invasive bladder cancer
The genetic mechanisms associated with progression of high-risk non-muscle-invasive bladder cancer (HR-NMIBC) have not been described. We conducted selective next-generation sequencing (NGS) of HR-NMIBC and compared the genomic profiles of cancers that responded to intravesical therapy and those that progressed to muscle-invasive or advanced disease. DNA was extracted from paraffin-embedded sec...
متن کاملManagement of high-risk non-muscle invasive bladder cancer.
Risk stratification is of paramount importance for the future treatment and follow-up of patients with transitional cell carcinoma (TCC) of the bladder. Transurethral resection (TUR) is the gold standard for initial diagnosis and treatment of non muscle invasive bladder cancer (NMIBC). Muscle must be present in the pathological specimen in order to correctly stage the tumor. When muscle is not ...
متن کاملTreatment of non-muscle-invasive bladder cancer
Ta tumors — Ta tumors are noninvasive papillary lesions that are confined to the urothelium and have not penetrated the basement membrane. These papillary tumors usually present as low-grade lesions that frequently recur multiple times prior to becoming invasive. The natural history of patients with Ta tumors without other evidence of invasive disease or Tis was illustrated by a retrospective s...
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ژورنال
عنوان ژورنال: Journal of Urology
سال: 2019
ISSN: 0022-5347,1527-3792
DOI: 10.1097/01.ju.0000555582.13406.9e