PCSK9 Expression in Epicardial Adipose Tissue: Molecular Association with Local Tissue Inflammation
نویسندگان
چکیده
منابع مشابه
Association of chemerin mRNA expression in human epicardial adipose tissue with coronary atherosclerosis
BACKGROUND Growing evidence suggests that epicardial adipose tissue (EAT) may play a key role in the pathogenesis and development of coronary artery disease (CAD) by producing several inflammatory adipokines. Chemerin, a novel adipokine, has been reported to be involved in regulating immune responses and glucolipid metabolism. Given these properties, chemerin may provide an interesting link bet...
متن کاملAssociation of epicardial adipose tissue thickness by echocardiography and hypertension.
OBJECTIVES Epicardial adipose tissue (EAT) is a component of visceral adiposity with endocrine and paracrine effects. It is also associated with metabolic syndrome (MetS). In this study, we investigated the relationship between EAT thickness and hypertension that is a component of MetS. STUDY DESIGN Enrolled in this study were 140 hypertensive patients and 60 age- and sex-similar normotensive...
متن کاملThe Association between Subclinical Hypothyroidism and Epicardial Adipose Tissue Thickness
BACKGROUND AND OBJECTIVES Subclinical hypothyroidism (SH) is considered to be a potential risk factor for cardiovascular disease. Epicardial adipose tissue (EAT) thickness is also closely related to cardiovascular disorders. The aim of this study was to evaluate whether SH is associated with higher EAT thickness. SUBJECTS AND METHODS Fifty-one consecutive patients with SH and 51 healthy contr...
متن کاملDecreased adiponectin and increased inflammation expression in epicardial adipose tissue in coronary artery disease
BACKGROUND Disorders of endocrine substances in epicardial adipose tissue are known causes of coronary artery disease (CAD). Adiponectin is associated with cardiovascular disease. However, expression of adiponectin in epicardial adipose tissue and its function in CAD pathogenesis is unclear. This study investigates adiponectin expression in epicardial adipose tissue in CAD patients. METHODS V...
متن کاملAssociation between omentin-1 expression in human epicardial adipose tissue and coronary atherosclerosis
BACKGROUND Omentin-1, a novel adipocytokine mainly expressed in visceral adipose tissue, has been found to inhibit the inflammatory response and improve insulin resistance as well as other obesity-related disorders. This study investigated the association between omentin-1 expression in human epicardial adipose tissue (EAT) and coronary atherosclerosis. METHODS Serum samples, and paired biops...
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ژورنال
عنوان ژورنال: Mediators of Inflammation
سال: 2020
ISSN: 0962-9351,1466-1861
DOI: 10.1155/2020/1348913