منابع مشابه
Complementary and alternative medicine patients are talking about: PC-SPES.
Digital Object Identifier: 10.1188/05.CJON.113-114 PC-SPES is an herbal supplement containing eight Chinese herbs (see Table 1). PC stands for prostate cancer, and spes is Latin for hope. PC-SPES was formulated according to traditional Chinese medicine principles involving ingredients that may counteract cytotoxic agents, minimize toxicity, and reduce the development of drug resistance in targe...
متن کاملIn vivo effect of PC-SPES on prostate growth and hepatic CYP3A expression in rats.
PC-SPES, a proprietary mixture composed of eight different herbs, is used worldwide as an alternative treatment by prostate cancer patients. It has been suggested that the clinical and in vitro antitumor activity exhibited by PC-SPES may be due to estrogenic activity, which in turn may be mediated by the presence of undeclared prescription drug contaminants. Here, we evaluated the in vivo effec...
متن کاملPC-SPES inhibits colon cancer growth in vitro and in vivo.
PC-SPES is a mixture of eight herbs with antiproliferative activity in prostate cancer cell lines and antitumor effects in animal models of prostate cancer. In addition, evidence of clinical efficacy in advanced prostate cancer has been reported. PC-SPES has also been shown to have antitumor activity against several other cancer cell lines including breast and neuroepithelial cancer, melanoma, ...
متن کاملClinical and biologic activity of an estrogenic herbal combination (PC-SPES) in prostate cancer.
BACKGROUND Herbal mixtures are popular alternatives to demonstrated therapies. PC-SPES, a commercially available combination of eight herbs, is used as a nonestrogenic treatment for cancer of the prostate. Since other herbal medicines have estrogenic effects in vitro, we tested the estrogenic activity of PC-SPES in yeast and mice and in men with prostate cancer. METHODS We measured the estrog...
متن کاملPC-SPES: A Potent Inhibitor of Nuclear Factor- B Rescues Mice from Lipopolysaccharide-Induced Septic Shock
Septic shock is the most common cause of death in intensive care units, and no effective treatment is available at present. Lipopolysaccharide (LPS) is the primary mediator of Gramnegative sepsis by inducing the production of macrophagederived proinflammatory cytokines, in which activation of nuclear factorB (NFB) plays an important role. PC-SPES is an eight-herb mixture active against a variet...
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ژورنال
عنوان ژورنال: Acta Oncologica
سال: 2004
ISSN: 0284-186X,1651-226X
DOI: 10.1080/02841860410018601