Patterns of co‐altered brain structure and function underlying neurological soft signs in schizophrenia spectrum disorders
نویسندگان
چکیده
منابع مشابه
Neurological soft signs and brain morphology in first-episode schizophrenia.
BACKGROUND Although minor motor and sensory deficits, or neurological soft signs (NSS), are a well-established finding in schizophrenia, the cerebral changes underlying these signs are only partly understood. We therefore investigated the cerebral correlates of NSS by using magnetic resonance imaging (MRI) in patients with schizophrenia and healthy controls. METHOD Forty-two patients, all rec...
متن کاملNeurological Soft Signs in First -Episode Schizophrenia
Neurological soft signs (NSS) refer to subtle neurological abnormalities comprising deficits in sensory integration, motor coordination, or sequencing of complex motor acts. It is generally accepted that NSS are more prevalent in schizophrenia patients, including first -episode cases, than in healthy subjects. Moreover, NSS have been consistently demonstrated in neuroleptic naïve firstepisode p...
متن کاملPotential endophenotype for schizophrenia: neurological soft signs.
INTRODUCTION Neurological soft signs (NSS) are suggested as a candidate endophenotype for schizophrenia. This article aims to review relevant literature and discuss the role of NSS in understanding schizophrenia. METHODS This is an update on a review article published in 2003. Articles from 2003 onwards were specifically reviewed and discussed with relevance to the role of NSS as endophenotyp...
متن کاملEarly signs in schizophrenia spectrum disorders.
The frequency of various early signs of illness was examined in 96 first-episode patients suffering from schizophrenia, schizoaffective, or schizophreniform disorder. A factor analysis of these early signs was performed, and each of the five dimensions identified was examined for its relation to symptoms of psychosis at presentation and after 1 year of treatment. The results suggested five prim...
متن کاملFirst Rank Symptoms and Neurological Soft Signs in Schizophrenia
The aim of the study was to compare the neurological soft signs (NSS) in schizophrenia patients with and without first rank symptoms (FRS), their first degree relatives (FDR), and normal controls. The study was conducted on 60 schizophrenia patients diagnosed according to ICD 10 DCR and categorized into groups with and without FRS using Schedules for Clinical Assessment in Neuropsychiatry, 30 F...
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ژورنال
عنوان ژورنال: Human Brain Mapping
سال: 2019
ISSN: 1065-9471,1097-0193
DOI: 10.1002/hbm.24755