Patterns of altered functional connectivity in mesial temporal lobe epilepsy
نویسندگان
چکیده
منابع مشابه
Altered Functional Connectivity and Small-World in Mesial Temporal Lobe Epilepsy
BACKGROUND The functional architecture of the human brain has been extensively described in terms of functional connectivity networks, detected from the low-frequency coherent neuronal fluctuations that can be observed in a resting state condition. Little is known, so far, about the changes in functional connectivity and in the topological properties of functional networks, associated with diff...
متن کاملDisrupted Causal Connectivity in Mesial Temporal Lobe Epilepsy
Although mesial temporal lobe epilepsy (mTLE) is characterized by the pathological changes in mesial temporal lobe, function alteration was also found in extratemporal regions. Our aim is to investigate the information flow between the epileptogenic zone (EZ) and other brain regions. Resting-state functional magnetic resonance imaging (RS-fMRI) data were recorded from 23 patients with left mTLE...
متن کاملTime-shift homotopic connectivity in mesial temporal lobe epilepsy.
BACKGROUND AND PURPOSE Voxel-mirrored intrinsic functional connectivity allows the depiction of interhemispheric homotopic connections in the human brain, whereas time-shift intrinsic functional connectivity allows the detection of the extent of brain injury by measuring hemodynamic properties. We combined time-shift voxel-mirrored homotopic connectivity analyses to investigate the alterations ...
متن کاملRole of resting state functional connectivity MRI in presurgical investigation of mesial temporal lobe epilepsy.
OBJECTIVE The authors aimed to determine the ability of resting-state functional connectivity MRI (fcMRI) to lateralise/localise the epileptogenic zone in patients presenting with mesial temporal lobe epilepsy (MTLE) at the individual level. METHODS Basal functional connectivity (BFC) was evaluated in each hemisphere of 22 MTLE patients. 200 volumes were acquired using a single-shot GE-EPI se...
متن کاملInfluence of Resting-State Network on Lateralization of Functional Connectivity in Mesial Temporal Lobe Epilepsy.
BACKGROUND AND PURPOSE Although most studies on epilepsy have focused on the epileptogenic zone, epilepsy is a system-level disease characterized by aberrant neuronal synchronization among groups of neurons. Increasingly, studies have indicated that mesial temporal lobe epilepsy may be a network-level disease; however, few investigations have examined resting-state functional connectivity of th...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2012
ISSN: 0013-9580
DOI: 10.1111/j.1528-1167.2012.03464.x