Patient-centered outcomes and trials of hydroxyethyl starch
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چکیده
منابع مشابه
Patient-centered outcomes and trials of hydroxyethyl starch
Meybohm and colleagues [1] propose that hydroxyethyl starch (HES) may be used safely in hypovolemic patients by applying a clinical algorithm and by restricting the dose administered. The authors question the validity of the results of the two trials that constitute over 60% of current data [2,3] and misleadingly state that in the Crystalloid vs. Hydroxyethyl Starch Trial (CHEST), HES administr...
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On Jan 26, 2018, the European Medicines Agency (EMA) suspended the marketing authorisations of hydroxyethyl starch (HES) solutions across the European Union.1 These intravenous solutions are often used for plasma volume replacement following acute blood loss. Evidence from highquality, investigator-initiated clinical trials in kidney donors, patients with sepsis, and in critically ill patients ...
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متن کاملRenal outcomes and mortality following hydroxyethyl starch resuscitation of critically ill patients: systematic review and meta-analysis of randomized trials
BACKGROUND Hydroxyethyl starch (HES) is a type of colloid fluid that is commonly used for volume resuscitation of patients admitted to the intensive care unit. Data regarding the renal consequences of HES are conflicting. PURPOSE To evaluate the effect of HES solutions on renal outcomes and mortality among critically ill patients requiring acute volume resuscitation. DATA SOURCES We searche...
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ژورنال
عنوان ژورنال: Critical Care
سال: 2013
ISSN: 1364-8535
DOI: 10.1186/cc13023